How Not Sleeping Is Taking Years off Your Life


The is an excerpt from Mercola.com on sleep and its importance:

Sleep and Memory Formation

In the featured video,2 Robert Stickgold, director of the Center for Sleep and Cognition at Beth Israel Deaconess Medical Center, discusses some of the lesser known reasons for why we need to sleep.3
Sleep is actually essential not just for cementing events into long-term memory, but also for making sense of your life. 
According to Stickgold, during sleep your brain "extracts the gist of what happened" to you during the day, and fosters insight into the workings of your life.
Essentially, during sleep, your brain pulls together and extracts meaning, while discarding unimportant details. In fact, sleep increases your ability to gain insights that would otherwise remain elusive by about 250 percent!
Dreaming plays a role in this process too. One test showed that thinking about correctly navigating through a maze really had no effect on performance. 
Ditto for taking a nap during which no dreaming was reported. Dreaming about navigating through the maze however, increased performance 10-fold!
According to Stickgold, the act of dreaming acts like a predictive marker, indicating that your brain is doing what it needs to do to successfully accomplish the task at hand.
These types of tests also showed that in the dream state, your brain is processing information at multiple levels. Your whole brain is engaged. So, during sleep, part of your brain is busy stabilizing, enhancing, and integrating new memories. It's also extracting rules, and the "gist" of what's going on. 
Then, during dreaming, old and new memories are integrated to form a new whole, and possible futures are imagined. This is what you actually perceive as "the action" of your dream. The sum total of these processes then allows you to see the meaning of your life. 

Less Sleep Results in Greater Calorie Consumption While Awake

On a more physical level, getting less than seven hours of sleep per night has been shown to raise your risk of weight gain, by increasing levels of appetite-inducing hormones. 
Recent research4 in which people's sleep and food intake was carefully tracked confirmed that more sleep correlated with fewer calories consumed, and vice versa. 
Most participants spread their eating and drinking over the course of 15 hours each day. About 25 percent of their daily calories were consumed before noon, and more than 35 percent after 6 pm. 
This kind of eating pattern is, I believe, a major reason why so many Americans struggle with their weight. They're grazing all day long, and eating a majority of their food far too close to bedtime. 
This flies in the face of our genetic ancestry, as our bodies are not designed to continuously receive calories. In fact, a number of beneficial effects take place when you go for periods of time without eating. This includes improved insulin and leptin sensitivity, which plays an important role in weight and health. 
Eating too close to bedtime also disrupts the function of your mitochondria, thereby speeding up cell damage and contributing to DNA mutations. Indeed, the benefits of restricting your eating to a narrower window each day are revealed in this study too. 
As reported by Reuters:5
"The researchers also tested whether the app might help people eat less by encouraging them to consume food and drink over a shorter stretch of the day. 
They asked eight overweight people who tended to eat over more than 14 hours of the day to cut back to 10 to 11 hours. After 16 weeks, these people lost about 3.5 percent of their excess body weight and reported sleeping better..."

Poor Sleep Raises Risk of Accidents and Depression 

Getting less than six hours of sleep leaves you cognitively impaired, which can have repercussions both at home, at work, and on the road. In 2013, drowsy drivers caused 72,000 car accidents in which 800 Americans were killed, and 44,000 were injured.6
Even a single night of sleeping only four to six hours can impact your ability to think clearly the next day. Lack of sleep has also been firmly linked to a heightened risk for depression.
Of the approximately 18 million Americans with depression, more than half of them struggle with insomnia. While it was long thought that insomnia was a symptom of depression, it now seems that insomnia may precede depression in some cases.7
Research has also found that sleep therapy resulted in remarkable improvements in depressed patients. About 70 percent of those with sleep apnea, whose sleep is repeatedly disrupted throughout the night, also tend to suffer from symptoms of depression.8
It's interesting to consider that if lack of sleep and lack of dreaming prevents you from seeing the meaning of your life, and prevents you from integrating memories and imagining possible futures (as discussed in the featured video), couldn't that play a significant role in fostering depression? I believe it could. 

Long-Term Sleep Deprivation Is a Risk Factor in Many Chronic Diseases

Over the long term, sleep deprivation — regardless of the cause — has been linked to a number of serious health effects, including but not limited to:
  • Diabetes. One of the most recent studies9 on this linked "excessive daytime sleepiness" with a 56 percent increased risk for type 2 diabetes
  • Decreased immune function. One recent study10 suggests deep sleep plays a role in strengthening immunological memories of previously encountered pathogens in a way similar to psychological long-term memory retention. In this way, your immune system is able to mount a much faster and more effective response when an antigen is encountered a second time
  • Cardiovascular and heart disease. In one study, women who got less than four hours of shut-eye per night doubled their risk of dying from heart disease.11 In a more recent study,12 adults who slept less than five hours a night had 50 percent more coronary calcium, a sign of oncoming heart disease, than those who regularly got seven hours.
    • Interestingly, sleeping more than nine hours a night was associated with 70 percent more calcium in the coronary arteries, compared to sleeping seven hours. The quality of sleep also had a big impact on blood vessel health. Those who reported sleeping poorly had 20 percent more arterial calcium than those who slept well. 
  • Alzheimer's.13 A number of studies have linked poor sleep or lack of sleep to an increased risk of Alzheimer's. One of the reasons for this has to do with the fact that the glymphatic system — your brain's waste removal system — only operates during deep sleep. Researchers have discovered14 that your blood-brain barrier tends to become more permeable with age, allowing more toxins to enter.
    • This, in conjunction with reduced efficiency of the glymphatic system due to lack of sleep, allows for more rapid damage to occur in your brain and this deterioration is thought to play a significant role in the development of Alzheimer's. 
  • Cancer. Tumors grow two to three times faster in laboratory animals with severe sleep dysfunctions. The primary mechanism thought to be responsible for this effect is disrupted melatonin production, a hormone with both antioxidant and anti-cancer activity. Melatonin both inhibits the proliferation of cancer cells and triggers cancer cell apoptosis (self-destruction). It also interferes with the new blood supply tumors required for their rapid growth (angiogenesis).  A number of studies have shown that night shift workers are at heightened risk of cancer for this reason.

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Sifu Marcus Lovemore

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